Harlequins scored first half tries as they went on to defeat Grenoble 38-20 in their European Rugby Challenge Cup clash at Twickenham Stoop on Saturday.

Agen managed to remain in course for a knock-out place in the ongoing European Challenge Cup competition following a 14-10 win over Grenoble at Stade Armandie on Friday.

Harlequins suffered their first defeat in the ongoing European Rugby Challenge Cup after they were beaten by Grenoble 19-13 at Stade des Alpes.

Grenoble have confirmed that Tonga international Sona Taumalolo has retired with immediate effect on medical grounds.

Grenoble scored three tries in the final quarter as they sealed a thrilling 31-27 win over Newcastle Falcons in their European Challenge Cup encounter at Stade des Alpes on Friday.

Scott Baldwin, Dan Evans and Hanno Dirksen scored doubles while Dan Biggar contrbuted with 21 points as Ospreys trounced Grenoble by 71-3 in their European Challenge Cup game at Liberty Stadium on Saturday.

Ospreys came with a nine-try riot as they trounced Grenoble with a 7-59 victory in their European Challenge Cup clash on Friday.

The European Challenge Cup game between Grenoble and Ospreys at Stade des Alpes on Thursday was postponed due to a frozen pitch.

Newcastle Falcons ran an eight-try riot to register their maiden victory in the European Challenge Cup 2016/17 after outclassing Grenoble by 50-7 at Kingston Park on Sunday.

Joe Marler could once again find himself the subject of a disciplinary enquiry after appearing to kick hooker Arnaud Heguy in the head during Harlequins' 30-6 romped past Grenoble to reach the European Challenge Cup final.

Nick Evans has battled back from a broken leg three weeks ahead of schedule and in time to feature in Harlequins' European Challenge Cup semi-final against Grenoble.

Jonathan Wisniewski kicked Grenoble to a one-point victory in the last European Rugby Challenge Cup as he bagged a 33-32 quarter-final win over Connacht.

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Harlequins will aim to preserve their perfect European Challenge Cup record this season when they tackle Calvisano in Italy on Saturday.

Edinburgh got back to winning ways in the European Rugby Challenge Cup after their defeat in last season's final against Gloucester while Brive beat Newcastle in tonight's matches.