Two tries from Darren Dawidiuk and Jonny May in the last five minutes of extra time gave Gloucester a 40-32 win over Connacht and a place in next week's Champions Cup play-off final.
Winning the European Rugby Challenge Cup, finishing ninth in the Aviva Premiership and with a Champions Cup play-off to come all represents a return to prominence for Gloucester Rugby Club in 2015.
Greig Laidlaw kicked 20 points in a man-of-the-match performance on Saturday afternoon as Gloucester beat London Irish 35 – 13 at Kingsholm in the penultimate round of the Aviva Premiership.
Gloucester survived Bill Meakes' red card to see off Edinburgh 19-13 and claim Challenge Cup glory at the Twickenham Stoop, reviving their Champions Cup qualification hopes at the expense of Sale and Harlequins.
Scotland captain Greig Laidlaw admits it will feel "a little bit strange" when he goes into European Challenge Cup final battle against his former team.
England international Ben Morgan has delivered an encouraging fitness bulletin as he continues to recover from a season-ending injury and retain the hope of keeping alive his World Cup dream.
Gloucester held off a stern challenge from Exeter to win their European Challenge Cup semi-final 30-19 at Kingsholm and set up a final clash with Edinburgh next month.
Gloucester head coach Laurie Fisher has underlined the magnitude of his team's task against reigning Aviva Premiership champions and runaway leaders Northampton on Saturday.
Wasps continued their impressive Premiership record at the Ricoh Arena as they downed Gloucester 32-21 to claim a fourth maximum points victory of the season.
England number eight Ben Morgan looks set to miss the entire RBS 6 Nations after breaking his leg in Gloucester's Aviva Premiership victory over Saracens on Friday night.