Wales international Dan Lydiate will miss the remainder of the ongoing season after picking a knee injury.
The 28-year-old suffered the blow in Wales' final autumn international game against South Africa and was replaced at the start of the second half.
The news was revealed by a statement released by his Pro 12 club Ospreys, who confirmed that Lydiate is suffering from anterior cruciate ligament. The injury has dampened his chances of featuring in the Six Nations tournament for Wales and British and Irish Lions tour of New Zealand in June 2017.
In a statement, the Ospreys said: "Dan Lydiate has been ruled out for the rest of the season after suffering anterior cruciate ligament damage in Wales' final autumn fixture against South Africa.
"Following consultation, it has been confirmed that surgery is required, as a result of which he will not play again until next season."
This was also Lydiate's second major injury this year. He was the go to man for Wales head coach Warren Gatland as he captained the side in the Old Mutual Wealth Cup clash against England in the absence of regular skipper Sam Warburton but missed the subsequent tour of New Zealand with injury.