The Rugby Football Union has unveiled the fixtures for the 2019/20 season that kicks-off on the third week of September.
The tournament will be spanned across 18 rounds with the final scheduled to be played on 30th May next year.
All 10 teams will continue to be part of the competition in a home and away contest with the top four teams progressing to the semi-final with the home grounds of the top two ranked sides being the venues.
“We’ve witnessed continued progress over the first two campaigns and know we’re in for another exciting seven months of rugby," said RFU Head of Women’s Performance Nicky Ponsford.
"We’ve seen some player movement in the off season so we are expecting the competition to be even tighter than it was last year which is great for all of us and really underlines how competitive the league has become .
“Last season, the standard of the league was fantastic and it was great to see so many players go on to represent the Red Roses and perform on the international stage.
“It’s a real whole-game effort and we are very much looking forward to continuing our work with clubs to help grow the women’s game.”
The opening round that kicks-off on 21st and 22nd September will see Bristol Bears hosting title holders Saracens while Loughborough Lightning, Firwood Waterloo, Wasps and Harlequins facing DMP Sharks, Gloucester-Hartpury, Worcester Warriors and Richmond respectively.
"We are incredibly proud of our partnership with the RFU, and to be sponsoring the inaugural elite women’s rugby competition, Tyrrells Premier 15s," said Tyrrells' Marketing Manager, Sarah Lawson.
“The past season has been fantastic with the introduction of the ground-breaking pro-contacts for the England Women’s team; a positive step that has changed the landscape of women’s rugby for the future.
"We are determined to continue helping the RFU increase participation and interest in the women’s game and encourage greater numbers of spectators to attend women’s matches.
“As another iconic English brand, we have built a great relationship with the RFU and look forward to the season ahead and taking the game to new heights.”