Saracens have forfeited their European Challenge Cup fixture against Pau due to positive Covid-19 cases in the English club.
The former European champions have reported a “significant number” of positive tests and have been under isolation along with close contacts.
The club also have shut their training ground with the staff members also now undergoing isolation.
“The club has taken the immediate action of closing the training ground and isolating all players, coaches and support staff," read a statement from Saracens.
“We have been working closely with EPCR and PRL (Premiership Rugby) and it is with regret that our game versus Section Paloise (Pau) in the EPCR Challenge Cup on Saturday 18th December has had to be forfeited by Saracens due to our inability to field a 23-man squad for this fixture.
“In addition to positive Covid-19 cases, we have players self-isolating due to being close contacts, and a number of players who are currently injured.
“This is extremely disappointing for everyone at the club, but as always the health and well-being of our people is our priority at this time.”
The rules for Covid affected games means Pau will be awarded a 28-0 victory which will be a big blow to Saracens, who started the campaign with a 18-21 defeat to Edinburgh.