England coach Eddie Jones has named Wasps back row Jack Willis as the replacement for Bath flanker Sam Underhill for the upcoming Six Nations tournament.
Underhill has sustained a hip injury which could possibly see him miss the entire Championship, although an official statement on his recovery time is yet to be announced.
The news follows a day after Joe Marler pulled out of the tournament due to personal reasons while Joe Launchbury was withdrawn from the squad due to a stress fracture on his leg.
Willis, who has played two Tests for England that came during the Autumn Nations Cup last year was already part of the shadow squad but now replaces Underhill in the main squad.
Exeter's Alec Hepburn, Northampton's Lewis Ludlam and David Ribbans have been added to the shadow squad as England are already without Mako Vunipola (injury) and Kyle Sinckler (suspended) apart from Marler and Launchbury.
England will kick-start their Six Nations campaign with a clash against Scotland on 6th February at Twickenham Stadium.
England's Six Nations squad:
Backs: Elliot Daly, Owen Farrell, George Ford, Ollie Lawrence, Max Malins, Jonny May, Paolo Odogwu, Harry Randall, Dan Robson, Henry Slade, Anthony Watson, Ben Youngs.
Forwards: Luke Cowan-Dickie, Tom Curry, Ben Earl, Ellis Genge, Jamie George, Jonny Hill, Maro Itoje, Charlie Ewels, Courtney Lawes, Tom West, Beno Obano, Will Stuart, Billy Vunipola, Harry Williams, Jack Willis, Mark Wilson.
Shadow squad: Charlie Atkinson, Ali Crossdale, Tom Dunn, George Furbank, Alex Hepburn, Joe Heyes, Jonathan Joseph, Lewis Ludlam, Joe Marchant, George Martin, Alex Mitchell, David Ribbans, Jacob Umaga