Ireland international Garry Ringrose will face up to six weeks on the sidelines following his latest injury setback.
Ringrose suffered a jaw injury in the recently concluded Six Nations game against Italy at Aviva Stadium on Saturday where he was forced to leave the field in the 27th minute.
The 25-year-old is now certain to miss the final round of the Six Nations clash for Ireland against France to be played in Paris next weekend and is also doubtful for the Autumn Nations Cup that begins on 13th November.
Ireland head coach Andy Farrell expressed disappointment on the news on Ringrose.
"Garry Ringrose has broken his jaw so bad news for us all," said Farrell.
"He's been so good for us the last 10 days, he has been absolutely fantastic with his leadership and he was a big part of the reason why we got what we wanted out of today.
"He was unfortunate with his thumb injury earlier in the Six Nations and has come back and had a setback like that which will keep him out for four to six weeks, so we're gutted for Garry."
Ringrose has played 29 Tests for Ireland since his debut in 2016 and was part of their World Cup campaign last year in Japan.