Ireland's plans for the upcoming November Test series have suffered a blow as Leinster's Ronan Kelleher has been ruled out following an ankle procedure.
Ireland have claimed the top position in the World Rugby Rankings following South Africa's defeat to Argentina in the fifth round of the Rugby Championship.
Ireland have consolidated their second position in the World Rugby Rankings while closing the gap over the top placed South Africa following their recent win in Durban.
Ciaran Frawley kicked two drop goals in the final 10 minutes as Ireland came from behind to edge out World Champions South Africa with a 25-24 margin in Durban to level the two-game series.
Ireland hooker Ronan Kelleher felt the squad has enough depth to overcome the setback of injury to Dan Sheenan as they take on the Springboks in the second Test on Saturday.
Ireland have suffered a double injury blow ahead of the second Test against South Africa with both hooker Dan Sheehan and scrumhalf Craig Casey ruled out due to injuries.
South Africa managed to hold off late fightback from Ireland as they sealed a thrilling 27-20 in the opening game of the two-match series in Pretoria on Saturday.
South Africa head coach Rassie Erasmus said he is expecting a stiff challenge from Ireland when the teams lock horns with each other in the two-game Test series.
South Africa head coach Rassie Erasmus has named two-time World Cup winning skipper Siya Kolisi as the captain for the upcoming series against Ireland.