Wales have released Dragons back-row Ross Moriarty from the Autumn Nations squad after he failed to recover from an ankle injury.
The 26-year-old last featured for Wales during the Six Nations tournament in March before the tournament came to suspension following the pandemic coronavirus and was forced to miss the final round of the tournament last month and also the opening two matches of the Autumn Nations Cup.
However, with not sufficient recovery, the Welsh Rugby Union has confirmed that Moriarty will miss the final two games of the autumn series as well.
Meanwhile, Taulupe Faletau, who missed the game against Georgia due to injury is expected to be available for the match against England while Justin Tipuric is undergoing return to play protocols after was struck by Georgia's Beka Saginadze.
Wales are at the third place in Group A of the Autumn Nations Cup table with a win and a defeat in the two games and their result against England this weekend will determine their opponent in the final round from Group B.