Shane Geraghty returns as one of five changes to the London Irish team which will face Edinburgh in Saturday's European Challenge Cup clash.
Geraghty starts at fly-half with the forward pack mostly unchanged. Tom Court, Gerard Ellis and Ben Franks pack down in the front row with Eoin Sheriff and Jebb Sinclair in the second row.
Conor Gilsenan comes in to make his first start of the season at openside flanker, Luke Narraway keeps the captaincy on the blind side and Ofisa Treviranus comes in at number eight.
Geraghty pairs with Brendan McKibbin in the halfbacks and Johnny Williams is back to join Aseli Tikoirotuma in the centres.
Andrew Fenby is another making his return to the starting line-up and he will take his place on the wing, with Alex Lewington and Sean Maitland completing the back three.
"We have welcomed some players back into the squad including Shane who is back from injury," head coach Tom Coventry explained.
"This is a big week for us returning to the Madejski Stadium; we want to go out there to make our supporters proud and give a good account of ourselves to stay in contention in the group."
London Irish side to face Edinburgh:
15. Sean Maitland; 14. Alex Lewington; 13. Aseli Tikoirotuma; 12. Johnny Williams; 11. Andrew Fenby; 10. Shane Geraghty; 9. Brendan McKibbin; 1. Tom Court; 2. Gerard Ellis; 3. Ben Franks; 4. Eoin Sheriff; 5. Jebb Sinclair; 6. Luke Narraway (captain); 7. Conor Gilsenan; 8. Ofisa Treviranus
Replacements: 16. Jimmy Stevens; 17. Tom Smallbone; 18. Leo Halavatau; 19. David Sisi; 20. Blair Cowan; 21. Darren Allinson; 22. Theo Brophy Clews; 23. Dominic Waldouck