Wales back row Taulupe Faletau has been ruled out of the remainder of ongoing Rugby World Cup campaign following a broken arm.
Faletau sustained the injury during the recently concluded fixture against Georgia where he left the field in the 69th minute. The news was confirmed by head coach Warren Gatland after the encounter which saw them seal a 43-19 victory to finish at the top of Pool C.
Wales will also be concerned about Gareth Anscombe, who was a late withdrawal ahead of the game with a groin injury.
"Toby has broken his arm so he'll be out," said Gatland.
"We're just going to assess Gareth over the next 72 hours. He's pulled his groin very high up. Talking to the medics, he's got a bit of power still in his leg which is a positive.
"It means he's not pulled it off the bone. We'll probably know in the next 48-72 hours what we need to do with him. Whether we've got time for him to recover or replace him directly.
"We've got to look at a replacement for Faletau, whether that's directly as a loose-forward replacement or whether we look at another position."
Liam Williams, who was one of the try-scorer in the game left the field on crutches after injuring a knee and Gatland is hopeful of his availability for the quarter-final game against Argentina.
"We've got a few sore players, particularly in the backs, after today's game. If you do see Liam Williams on crutches, it's not that he's done anything significantly bad. He got a whack on the knee and the medics, from a comfort perspective, have put him on crutches to save him walking around a bit.
"He's got a knock and probably won't take a huge part in training in the early part of next week. But hopefully he'll be fit for the quarterfinal."