Harlequins have made five changes to the starting line up for the 11th round of the Gallagher Premiership game against Northampton Saints at Twickehnam on Monday.
Fly-half Marcus Smith and backrow James Chisholm both have tested positive for Covid-19 earlier in the week will miss the game with Will Edwards taking the fly-half role.
Joe Marler and Will Collier return to the front row joining Jack Walker and are the preferred props replacing Santiago Garcia Botta and Simon Kerrod respectively.
Matt Symons makes a comeback at second row joining skipper Stephan Lewies with Hugh Tizard dropping out of the matchday squad. The final change sees Louis Lynagh restored at right wing with Joe Marchant making a positional change to midfield joining Joe Marchant.
Harlequins: 15 Tyrone Green, 14 Louis Lynagh, 13 Joe Marchant, 12 Andre Esterhuizen, 11 Cadan Murley, 10 Will Edwards, 9 Danny Care, 8 Alex Dombrandt, 7 Jack Kenningham, 6 Tom Lawday, 5 Stephan Lewies (c), 4 Matt Symons, 3 Will Collier, 2 Jack Walker, 1 Joe Marler
Reserves: 16 Jack Musk, 17 Santiago Garcia Botta, 18 Simon Kerrod, 19 Hugh Tizard, 20 Dino Lamb, 21 Lewis Gjaltema, 22 Luke Northmore, 23 Huw Jones
Northampton: 15 George Furbank, 14 Ollie Sleightholme, 13 Matt Proctor, 12 Fraser Dingwall, 11 Courtnall Skosan, 10 Dan Biggar, 9 Alex Mitchell, 8 Juarno Augustus, 7 Lewis Ludlam (c), 6 Courtney Lawes, 5 Api Ratuniyarawa, 4 David Ribbans, 3 Ehren Painter, 2 Sam Matavesi, 1 Alex Waller
Reserves: 16 Mike Haywood, 17 Nick Auterac, 18 Paul Hill, 19 Alex Coles, 20 Tom Wood, 21 Tom James, 22 Rory Hutchinson, 23 Ahsee Tuala