England will be without their talented fly-half Marcus Smith for the second round of the Six Nations to be played at Twickenham Stadium on Saturday.
The decision follows after the Harlequins star has not made sufficient recovery from a calf injury that he sustained in a training session and had already missed the tournament opening game against Italy.
In the absence of Smith, George Ford started for the game against the Azzurri while Fin Smith made his debut after coming off the bench in the final 14 minutes.
Meanwhile, Ellis Genge, who sustained a foot injury during the game against Italy has been named in the 36-man squad.
"I'd be really hopeful that Ellis is available for next weekend," said England head coach Steve Borthwick.
"He trained on Thursday and felt something. He had a scan on his foot on Friday morning. There was a small, acute recurrence of something that happened in the past."
Following their 27-24 win over Italy in the opening round, England are at second place in the Six Nations table with four points.
England 36-man squad:
Forwards: Jamie Blamire, Ollie Chessum, Dan Cole, Alex Coles, Chandler Cunningham-South, Ben Curry, Theo Dan, Alex Dombrandt, Ben Earl, Charlie Ewels, Ellis Genge, Jamie George, Joe Heyes, Maro Itoje, Joe Marler, Beno Obano, Tom Pearson, Ethan Roots, Will Stuart, Sam Underhill
Backs: Oscar Beard, Danny Care, Elliot Daly, Fraser Dingwall, Immanuel Feyi-Waboso, George Ford, Tommy Freeman, George Furbank, Alex Mitchell, Will Muir, Max Ojomoh, Tom Roebuck, Henry Slade , Fin Smith, Ben Spencer, Freddie Steward