Argentina head coach Mario Ledesma has made a total of 10 changes to the line-up that will take on Barbarians in the Killik Cup game at Twickenham on Saturday.
Juan Pablo Zeiss, Julian Montoya, Matias Alemanno and Tomas Lezana return to the pack replacing Santiago Garcia Botta, Agustin Creevy, Tomas Lavanini and Javier Ortega Desio.
Meanwhile, Bautista Ezcurra, Matias Orlando, Sebastian Cancelliere and Juan Cruz Mallia return in the backs that sees only Ramiro Moyano retaining his place.
Argentina are yet to win a game in the November series after they were earlier defeated by Ireland, France and Scotland a and Ledesma will be hoping to mark an end to 2018 with a victory.
Argentina: Juan Cruz Mallia, Sebastian Cancelliere, Matias Orlando, Bautista Ezcurra, Ramiro Moyano, Joaquin Diaz Bonilla, Martin Landajo, Rodrigo Bruni, Tomas Lezana, Pablo Matera (c), Matias Alemanno, Guido Petti, Santiago Medrano, Julian Montoya, Juan Pablo Zeiss
Replacements: Agustin Creevy, Mayco Vivas, Lucio Sordoni, Tomas Lavanini, Santiago Grondona, Tomas Cubelli, Jeronimo de la Fuente, Santiago Carreras