Wales international Bradley Davies will miss the end of the year series for his country following a knee surgery.
The news was confirmed by Ospreys' medical performance manager Chris Towers, who revealed that the 31-year-old 'underwent surgery for a cartilage problem in the knee' and will need up to four months of rehabilitation period.
"Bradley underwent surgery for a cartilage problem in the knee last week," Towers said.
"Taking on board guidelines, he is looking at being available for selection in three to four months' time."
As a result, Davies was released from Wales' autumn international squad leaving head coach Warren Gatland with skipper Alun Wyn Jones, Cory Hill, Jake Ball and Adam Beard as the options for number four and five slots.
Davies has played 64 Tests for Wales since his debut in 2009 and was part of the summer series campaign in the games against South Africa and Argentina.
Gatland's men will face Scotland, Australia, Tonga and South Africa in their autumn international campaign on 3rd, 10th, 17th and 24th November respectively with all the games scheduled at Millennium Stadium.