Juan Martin Hernandez replaces Nicolas Sanchez at fly-half for Argentina

Juan Martin Hernandez will start at fly-half for Argentina on Saturday's clash against England at Twickenham taking over from Nicolas Sanchez.

Hernandez, who has been capped 65 times for the Pumas will move from midfield to replace fly-half Sanchez, who is out of matchday 23 with Santiago Gonzalez Iglesias recalled to centre.

Argentina head coach Daniel Hourcade has made two other changes to the line-up that lost narrowly to Scotland last weekend.

Leonardo Senatore has taken the place Facundo Isa in the back row, while Tomas Cubelli has been preferred at scrum-half over Martin Landajo.

Hourcade is confident that Hernandez will deliver at fly-half considering his vast experience.

"Having Hernandez in the starting line-up is always a benefit for the team and of course playing at 10 is a position that he prefers.

"It is not only Hernandez's experience of that game which is important, it is his knowledge, his experience in many situations that is important for the team."

Argentina team: J Tuculet (Jaguares); M Orlando (Jaguares), M Moroni (Jaguares), S Gonzalez Iglesias (Jaguares), S Cordero (Jaguares); J M Hernandez (Jaguares) T Cubelli (Brumbies); L Noguera (Jaguares), A Creevy (Jaguares, captain), R Herrera (Jaguares), G Petti (Jaguares), M Alemanno (Jaguares), P Matera (Jaguares), J Ortega Desio (Jaguares), L Senatore (Jaguares).

Replacements: J Montoya (Jaguares), S Garcia Botta (Jaguares), E Pieretto (Jaguares), F Isa (Jaguares), T Lezana (Jaguares), M Landajo (Jaguares), J De La Fuente (Jaguares), J P Estelles (Northampton).